Moving away from JavaScript today, but not the web, I have a list of some alternative .NET projects for delivering web based content.
Service Stack
http://www.servicestack.net/
Thoughtfully architected, obscenely fast, thoroughly enjoyable web services for all. Tooling to augment or replace ASP.NET MVC or WCF for various web related tasks.
Nancy
http://nancyfx.org/
A lightweight framework for building HTTP based services, inspired by Sinatra (hence the name)
Oak
http://amirrajan.github.io/Oak/
Frictionless development for ASP.NET MVC single page web apps. Prototypical and dynamic capabilities brought to C#. Watch some of the videos (the first one is a nice example of a smooth development workflow).
Simple.Data
https://github.com/markrendle/Simple.Data
A light-weight, dynamic data access component for C# 4.0. If you want a simple way to get at data stored in a wide variety of relational and nosql sources, then take a look.
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